Product ID:PROTEASE TYPE XIV BACTERIAL FROM STREPTOMYCES GRISEUS, P5147
MSDS Date:01/01/1995
FSC:6505
NIIN:00N093329
Status Code:A
MSDS Number: CJXVG

Emergency Phone: 314-771-5765

Info Phone: 314-771-5765

Cage: 21076

Telephone: 314-771-5765

Cage: 21076

(ORAL,RAT) 3290

CAS: 9036-06-0

RTECS: UK9595000

LD50 LC50 Mixture:SEE INGREDIENTS & TOXICOLOGICAL INFO.
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE: HARMFUL IF INHALED. MAY BE
HARMFUL IF SWALLOWED. MAY BE HARMFUL IS ABSORBED THROUGH SKIN.
CAUSES IRRITATION. MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND
UPPER RESPIRATORY TRACT. MAY CAUSE AL LERGIC RESPIRATORY AND SKIN
REACTIONS. REPEATED EXPOSURE CAN CAUSE: ASTHMA. TARGET ORGAN(S):
LUNGS. NERVOUS SYSTEM, KIDNEYS.
Effects of Overexposure:SEE HEALTH HAZARDS.

First Aid:INGESTION: WASH OUT MOUTH WITH WATER PROVIDED PERSON IS
CONSCIOUS. CALL MD. SKIN: FLUSH WITH COPIOUS AMOUNTS OF WATER FOR
AT LEAST 15 MINUTES. REMOVE CONTAMINATED CLOTHING AND SHOES. CALL
MD. INHALATI ON: REMOVE TO FRESH AIR. IF BREATHING BECOMES
DIFFICULT, CALL MD. EYES: FLUSH WITH COPIOUS AMOUNTS OF WATER FOR
AT LEAST 15 MINUTES. ASSURE ADEQUATE FLUSHING BY SEPARATING THE
EYELIDS WITH FINGERS. CA LL MD.

Extinguishing Media:WATER SPRAY, CARBON DIOXIDE, DRY CHEMICAL POWDER OR
APPROPRIATE FOAM.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
EQUIPMENT .

Spill Release Procedures:WEAR NIOSH APPROVED SELF-CONTAINED BREATHING
APPARATUS, RUBBER BOOTS AND HEAVY RUBBER GLOVES. SWEEP UP, PLACE IN
A BAG AND HOLD FOR WASTE DISPOSAL. AVOID RAISING DUST. VENTILATE
AREA AND WASH SPILL SI TE AFTER MATERIAL PICKUP IS COMPLETE.

Handling and Storage Precautions:DO NOT BREATHE DUST. HANDLE IN A
CLOSED SYSTEM.
Other Precautions:HARMFUL. HARMFUL BY INHALATION. MAY CAUSE
SENSITIZATION BY INHALATION AND SKIN CONTACT. IRRITATING TO EYES,
RESPIRATORY SYSTEM AND SKIN.

Respiratory Protection:WEAR APPROPRIATE NIOSH APPROVED RESPIRATOR.
Ventilation:USE ONLY IN A CHEMICAL FUME HOOD.
Protective Gloves:CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:EYE WASH AND DELUGE SHOWER MEETING ANSI
DESIGN CRITERIA . WEAR SUITABLE OTHER PROTECTIVE CLOTHING.
Supplemental Safety and Health

Appearance and Odor:SOLID.

Stability Indicator/Materials to Avoid:YES
Hazardous Decomposition Products:NATURE OF DECOMPOSITION PRODUCTS NOT
KNOWN.
Conditions to Avoid Polymerization:WILL NOT OCCUR.

Waste Disposal Methods:DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE
SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL
ENVIRONMENTAL REGULATIONS.

Toxicological Information:THE TOXICOLOGICAL PROPERTIES HAVE NOT BEEN
THOROUGHLY INVESTIGATED. MAY BE MORE POTENT AND BROADER IN
SPECIFICITY THAN OTHER PROTEASES. TOXICITY DATA: LD50:(ORAL,RAT)
3290 MG/KG; LD50:(IPR,RAT) 16,200 UG/KG; LD50:(SCU,RAT) 100 MG/KG;
LD50:(IVN,RAT) 15,800 UG/KG; LD50:(ORAL,MUS) 4010 MG/KG;
LD50:(IPR,MUS) 14,100 UG/KG; LD50:(SCU,MUS) 26,800 UG/KG;
LD50:(IVN,MUS) 20,500 UG/KG - NIIRDN 6,730,82. ONLY SELECTED
REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES (RTECS) DATA IS
PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR COMPLETE INFORMATION.

Ecological:DATA NOT YET AVAILABLE.

Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION
INFORMATION.

SARA Title III Information:DATA NOT AVAILABLE.
Federal Regulatory Information:DATA NOT AVAILABLE.
State Regulatory Information:DATA NOT AVAILABLE.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.